ลงมือ(long meu)

Meanings

1VerbB1

[to] start doing; get to work

to begin taking action on a task; to set about doing something

2VerbB2

[to] take action (often decisive)

to proceed to act, sometimes implying hands-on or immediate action

Examples

If you're ready, proceed to tackle the problem now; don't wait for it to escalate.